CAS No. 1113-59-3

Batch: Purity:98
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Bromopyruvic acid (3-BP) Chemical Structure
Chemical Structure
Check the Bromopyruvic acid (3-BP) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1113-59-3
Molecular Formula

C3H3BrO3
Molecular Weight (MW) 166.96
SMILES C(C(=O)C(=O)O)Br

Ordering Information

Biological Activity

Bromopyruvic acid is a hexokinase II inhibitor that disrupts tumor cell energy metabolism. By inhibiting hexokinase II and suppressing glycolysis, it depletes intracellular ATP production in cancer cells. This metabolic impairment leads to the inhibition of tumor growth and the induction of cell death, making it an effective agent for targeting glycolysis-dependent malignancies. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 33 mg/mL (197.65 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 33 mg/mL
Ethanol 33 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.