CAS No. 3572-43-8
Batch:
Purity:99.68
Chemical Structure
Check the
Bromhexine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 3572-43-8 | |
|---|---|---|
| Molecular Formula |
C14H20Br2N2 |
|
| Molecular Weight (MW) | 376.13 | |
| SMILES | CN(CC1=C(C(=CC(=C1)Br)Br)N)C2CCCCC2 |
Bromhexine is a mucolytic agent and expectorant that acts as an inhibitor of transmembrane protease serine 2 (TMPRSS2). It enhances bronchial secretion and decreases mucus viscosity, thereby promoting sputum clearance and improving respiratory tract dynamics. By targeting TMPRSS2, bromhexine disrupts downstream proteolytic cascades involved in prostate cancer cell invasion and viral activation, leading to reduced cellular metastasis and attenuated tissue inflammation. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
75 mg/mL
(199.39 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 75 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.