CAS No. 70359-46-5

Batch: Purity:99.92
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Brimonidine Tartrate Chemical Structure
Chemical Structure
Check the Brimonidine Tartrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine;(2R,3R)-2,3-dihydroxybutanedioic acid
CAS Number 70359-46-5
Molecular Formula

C15H16BrN5O6
Molecular Weight (MW) 442.22
SMILES C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br.C(C(C(=O)O)O)(C(=O)O)O
InChIKey QZHBYNSSDLTCRG-LREBCSMRSA-N

Biological Activity

Brimonidine Tartrate is a potent and highly selective alpha2-adrenergic receptor agonist. Selective activation of alpha2-adrenergic receptors inhibits adenylate cyclase activity, leading to a decrease in intracellular cyclic AMP levels. This modulation of adrenergic signaling pathways reduces aqueous humor production and enhances uveoscleral outflow, resulting in decreased intraocular pressure and effective management of ocular hypertension.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 88 mg/mL (198.99 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 22 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.