CAS No. 224047-41-0
Batch:
Purity:99.94
Chemical Structure
Check the
Brassinazole
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 4-(4-chlorophenyl)-2-phenyl-3-(1,2,4-triazol-1-yl)butan-2-ol | |
|---|---|---|
| CAS Number | 224047-41-0 | |
| Molecular Formula |
C18H18ClN3O |
|
| Molecular Weight (MW) | 327.81 | |
| SMILES | CC(C1=CC=CC=C1)(C(CC2=CC=C(C=C2)Cl)N3C=NC=N3)O | |
| InChIKey | YULDTPKHZNKFEY-UHFFFAOYSA-N |
Biological Activity
Brassinazole is a triazole-type brassinosteroid biosynthesis inhibitor with an IC50 of approximately 1 μM. By blocking cytochrome P450-mediated brassinosteroid biosynthesis, it suppresses brassinosteroid signaling. This inhibition impairs key physiological processes in plants, leading to characteristic phenotypes such as reduced stem elongation, leaf dwarfism, and suppressed cell division. Brassinazole serves as a valuable chemical tool for elucidating brassinosteroid-dependent physiological pathways. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
66 mg/mL
(201.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 4 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.