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bpV(phen)

Cat.No.E7665

bpV(phen), a insulin-mimetic agent, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP-β and PTP-1B, respectively. This compound inhibits proliferation of the protozoan parasite Leishmania in vitro. It strongly induces the secretion of a large number of chemokines and pro-inflammatory cytokines, and it activates a Th1-type pathway (IL-12, IFNγ). This chemical can also induce cell apoptosis, and has anti-angiogenic and anti-tumor activity.
bpV(phen) Chemical Structure

Chemical Structure

Molecular Weight: 350.24

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Quality Control

Chemical Information, Storage & Stability

Molecular Weight 350.24 Formula Storage (From the date of receipt)
CAS No. 42494-73-5 -- Storage of Stock Solutions Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Mechanism of Action

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