SMILES:
C1=CC(=CC(=C1)Cl)C2=NC(=CC(=C2)CC3=CC=C(C=C3)CC(=O)O)C(F)(F)F
Chemical Structure
Check the
Zatolmilast (BPN14770)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-[4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]phenyl]acetic acid | |
|---|---|---|
| CAS Number | 1606974-33-7 | |
| Molecular Formula |
C21H15ClF3NO2 |
|
| Molecular Weight (MW) | 405.80 | |
| SMILES | C1=CC(=CC(=C1)Cl)C2=NC(=CC(=C2)CC3=CC=C(C=C3)CC(=O)O)C(F)(F)F | |
| InChIKey | LTSUMTMGJHPGFX-UHFFFAOYSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
81 mg/mL
(199.6 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 81 mg/mL |
| Water | ˂1 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Zatolmilast (BPN14770) Clinical Trials
- Zatolmilast (BPN14770) Solubility in DMSO
- Zatolmilast (BPN14770) Stock Solution
- Zatolmilast (BPN14770) Storage
- Zatolmilast (BPN14770) Stability
- Zatolmilast (BPN14770) Molecular Weight
- Zatolmilast (BPN14770) CAS Number
- Zatolmilast (BPN14770) Chemical Structure (2D and 3D)
- Zatolmilast (BPN14770) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.