SMILES:

CN1CCN(CC1)C2=NC=C(OC3=NC(=CC(=C3)CN4CCC(CC4)CC(O)=O)C5=CC(=CC(=C5)Cl)Cl)C=N2
BOS-318 Chemical Structure
Chemical Structure
Check the BOS-318 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-[1-[[2-(3,5-dichlorophenyl)-6-[2-(4-methylpiperazin-1-yl)pyrimidin-5-yl]oxy-4-pyridinyl]methyl]piperidin-4-yl]acetic acid
CAS Number 2387633-15-8
Molecular Formula

C28H32Cl2N6O3
Molecular Weight (MW) 571.5
SMILES CN1CCN(CC1)C2=NC=C(OC3=NC(=CC(=C3)CN4CCC(CC4)CC(O)=O)C5=CC(=CC(=C5)Cl)Cl)C=N2
InChIKey AZEJIKZNBHEXCM-UHFFFAOYSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (174.97 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.