CAS No. 1771691-34-9
Chemical Structure
Check the
BMS-986202
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 6-(cyclopropanecarbonylamino)-4-[3-(5-fluoropyrimidin-2-yl)-2-methoxyanilino]-N-(trideuteriomethyl)pyridine-3-carboxamide | |
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| CAS Number | 1771691-34-9 | |
| Molecular Formula |
C22H18D3FN6O3 |
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| Molecular Weight (MW) | 439.46 | |
| InChIKey | BBRMAVGRWHNAIG-FIBGUPNXSA-N |
BMS-986202 is a potent, selective, and orally active tyrosine kinase 2 (TYK2) inhibitor that targets the TYK2 pseudokinase domain (JH2). By binding allosterically to the JH2 regulatory domain, it stabilizes an inactive conformation to suppress TYK2 kinase activity and disrupt receptor-mediated JAK/STAT signaling pathways. Consequently, BMS-986202 inhibits downstream STAT phosphorylation, suppressing cytokine-induced pro-inflammatory gene expression and cellular responses. [1]
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Note: Technical data last updated: Sep 1, 2026.