CAS No. 132810-10-7
| CAS Number | 132810-10-7 | |
|---|---|---|
| Molecular Formula |
C23H30FN3 |
|
| Molecular Weight (MW) | 367.5 | |
| SMILES | CCN1CCN(CC1)C2=NC3=C(CCCCCC3)C(=C2)C4=CC=C(C=C4)F |
Blonanserin is a relatively selective dopamine D2 receptor and serotonin 5-HT2A receptor antagonist. By inhibiting dopamine D2 and 5-HT2A receptor-mediated signaling pathways, blonanserin modulates dopaminergic and serotonergic neurotransmission in the central nervous system. This antagonist activity regulates downstream signaling cascades involved in behavioral control and neurological function, demonstrating efficacy in experimental models of schizophrenia and psychosis.
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Concentration
Volume
Mass
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|---|
| Solvent | Solubility & Note |
|---|---|
| 5%TFA | 3 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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