CAS No. 80-05-7

Batch: Purity:99.59
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Bisphenol A Chemical Structure
Chemical Structure
Check the Bisphenol A product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol
CAS Number 80-05-7
Molecular Formula

C15H16O2
Molecular Weight (MW) 228.29
SMILES CC(C)(C1=CC=C(C=C1)O)C2=CC=C(C=C2)O
InChIKey IISBACLAFKSPIT-UHFFFAOYSA-N

Ordering Information

Biological Activity

Bisphenol A is a xenoestrogen compound that functions as an agonist targeting estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ). By binding to these estrogen receptors, it modulates downstream estrogenic signaling pathways, altering gene transcription and inducing hormone-like endocrine disruptive downstream phenotypes in various cell types. These biological activities affect intracellular signaling cascades including ER-mediated transcriptional activity and cellular proliferation. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 46 mg/mL (201.49 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 46 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.