CAS No. 66722-44-9
Batch:
Purity:
Chemical Structure
Check the
Bisoprolol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 66722-44-9 | |
|---|---|---|
| Molecular Formula |
C18H31NO4 |
|
| Molecular Weight (MW) | 325.44 | |
| SMILES | CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O |
Biological Activity
Bisoprolol is a potent and highly selective β1-adrenergic receptor antagonist. By selectively inhibiting β1-adrenoceptors, it blocks catecholamine-stimulated activation of adenylate cyclase and reduces intracellular cyclic AMP (cAMP) production in cardiac tissue. This blockade attenuates downstream signal transduction, leading to decreased cardiac contractility, reduced heart rate, and diminished myocardial oxygen demand. [1]
How to Prepare Stock Solution?
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Concentration
Volume
Mass
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Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
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Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.