CAS No. 1420071-30-2
Batch:
Purity:98
Chemical Structure
Check the
Bioymifi
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 5-[5-[(Z)-[3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]isoindole-1,3-dione | |
|---|---|---|
| CAS Number | 1420071-30-2 | |
| Molecular Formula |
C22H12BrN3O4S |
|
| Molecular Weight (MW) | 494.32 | |
| SMILES | C1=CC(=CC=C1N2C(=O)C(=CC3=CC=C(O3)C4=CC5=C(C=C4)C(=O)NC5=O)SC2=N)Br | |
| InChIKey | ULBOWKXOFOTCMU-NLDKGBHCSA-N |
Bioymifi is a small-molecule death receptor 5 (DR5) agonist that specifically binds to the extracellular domain of DR5 with a Kd ofwhile exhibiting minimal binding affinity for DR4. Upon target engagement, Bioymifi induces DR5 clustering and receptor aggregation, thereby activating the downstream TRAIL signaling pathway to trigger caspase-dependent extrinsic apoptosis in cancer cells. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
43 mg/mL
(86.98 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.