Catadegbrutinib (BGB-16673): Selectivity & Specificity
Catadegbrutinib (BGB-16673) is a potent inhibitor of BTK (0.69 ± 0.091 nM), CRBN-DBB1 complex (316 ± 82 nM). Catadegbrutinib (BGB-16673) exhibits the greatest inhibitory potency toward BTK (IC50 = 0.69 ± 0.091 nM).