CAS No. 42864-78-8
Batch:
Purity:99.07
Chemical Structure
Check the
Bevantolol hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 42864-78-8 | |
|---|---|---|
| Molecular Formula |
C20H27NO4.HCl |
|
| Molecular Weight (MW) | 381.89 | |
| SMILES | CC1=CC(=CC=C1)OCC(CNCCC2=CC(=C(C=C2)OC)OC)O.Cl |
Bevantolol hydrochloride is a cardioselective beta-1 adrenoceptor antagonist possessing weak membrane-stabilizing activity. By selectively targeting beta-1 adrenergic receptors, it blocks catecholamine-mediated adrenergic signal transduction. In cardiovascular tissues, this inhibition attenuates downstream cyclic AMP (cAMP) signaling pathways, leading to reduced cardiac contractility and modulation of vascular tone while lacking intrinsic sympathomimetic activity.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
76 mg/mL
(199.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 61 mg/mL |
| Water | 52 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Bevantolol hydrochloride Solubility in DMSO
- Bevantolol hydrochloride Stock Solution
- Bevantolol hydrochloride Storage
- Bevantolol hydrochloride Stability
- Bevantolol hydrochloride Molecular Weight
- Bevantolol hydrochloride SMILES
- Bevantolol hydrochloride Chemical Structure (2D and 3D)
- Bevantolol hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.