CAS No. 138-92-1
Batch:
Purity:99.94
Chemical Structure
Check the
Betazole Dihydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 138-92-1 | |
|---|---|---|
| Molecular Formula |
C5H11Cl2N3 |
|
| Molecular Weight (MW) | 184.07 | |
| SMILES | C1=C(NN=C1)CCN.Cl.Cl |
Betazole dihydrochloride (Ametazole) is a selective histamine H2 receptor agonist. Activation of the histamine H2 receptor stimulates adenylate cyclase activity, leading to increased intracellular cyclic AMP levels and activation of protein kinase A. This signaling cascade triggers parietal cell activation and stimulates gastric acid secretion. Betazole is widely utilized as a pharmacological agent to evaluate gastric secretory function in experimental models and clinical diagnostics.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
37 mg/mL
(201.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 37 mg/mL |
| Ethanol | 18 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Betazole Dihydrochloride Solubility in DMSO
- Betazole Dihydrochloride Stock Solution
- Betazole Dihydrochloride Storage
- Betazole Dihydrochloride Stability
- Betazole Dihydrochloride Molecular Weight
- Betazole Dihydrochloride SMILES
- Betazole Dihydrochloride Chemical Structure (2D and 3D)
- Betazole Dihydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.