CAS No. 63659-19-8
Batch:
Purity:99.46
Chemical Structure
Check the
Betaxolol HCl
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 63659-19-8 | |
|---|---|---|
| Molecular Formula |
C18H29NO3.HCl |
|
| Molecular Weight (MW) | 343.89 | |
| SMILES | CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O.Cl |
Betaxolol HCl is a selective β1 adrenergic receptor antagonist that targets β1 adrenergic receptors. By blocking β1 adrenergic receptor activation, it suppresses intracellular cAMP accumulation and downstream protein kinase A activity. This inhibition reduces aqueous humor secretion and cardiac cell responsiveness, thereby modulating sympathetic signaling pathways in cellular and cardiovascular research models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
69 mg/mL
(200.64 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 69 mg/mL |
| Ethanol | 69 mg/mL |
| DMSO |
69 mg/mL
(200.64 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 69 mg/mL |
| Ethanol | 69 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.