CAS No. 54856-23-4
Batch:
Purity:98
Chemical Structure
Check the
Betahistine mesylate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 54856-23-4 | |
|---|---|---|
| Molecular Formula |
C8H12N2.2CH4O3S |
|
| Molecular Weight (MW) | 328.41 | |
| SMILES | CNCCC1=CC=CC=N1.CS(=O)(=O)O.CS(=O)(=O)O |
Betahistine mesylate is a histamine analog that functions as a histamine H1 receptor agonist and histamine H3 receptor antagonist. It modulates the histaminergic system by stimulating H1 receptors to induce vasodilation and blocking H3 autoreceptors to enhance histamine release. These actions lead to improved microcirculation in the inner ear and modulation of vestibular neurotransmission. [1][2]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
65 mg/mL
(197.92 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.