CAS No. 633-66-9
Batch:
Purity:99.87
Chemical Structure
Check the
Berberine Sulfate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 633-66-9 | |
|---|---|---|
| Molecular Formula |
C20H18NO4.HO4S |
|
| Molecular Weight (MW) | 433.43 | |
| SMILES | COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC.OS(=O)(=O)[O-] |
Berberine sulfate is a natural plant-derived isoquinoline alkaloid that exhibits broad-spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria, fungi, and protozoa. As a potent AMP-activated protein kinase (AMPK) activator, it modulates key downstream metabolic and cell signaling pathways, resulting in reduced lipid accumulation, attenuated inflammatory responses, and suppressed proliferation of pathogenic microorganisms. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
11 mg/mL
(25.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
20 mg/mL
(46.14 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.