CAS No. 113-98-4

Batch: Purity:99.87
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Benzylpenicillin potassium Chemical Structure
Chemical Structure
Check the Benzylpenicillin potassium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
CAS Number 113-98-4
Molecular Formula

C16H17N2O4S.K
Molecular Weight (MW) 372.48
SMILES CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[K+]
InChIKey IYNDLOXRXUOGIU-LQDWTQKMSA-M

Ordering Information

Biological Activity

Benzylpenicillin potassium is a broad-spectrum beta-lactam antibiotic that targets bacterial penicillin-binding proteins (PBPs). By selectively binding to PBPs, it inhibits transpeptidase activity and prevents the cross-linking of peptidoglycan chains during bacterial cell wall biosynthesis. This structural disruption weakens bacterial cell walls, leading to increased osmotic permeability, cell lysis, and bacterial cell death in susceptible organisms.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 74 mg/mL (198.66 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 74 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.