CAS No. 14098-44-3

Batch: Purity:99.84
Check CoA
Benzo-15-crown-5-ether (B15C5) Chemical Structure
Chemical Structure
Check the Benzo-15-crown-5-ether (B15C5) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 14098-44-3
Molecular Formula

C14H20O5
Molecular Weight (MW) 268.31

Ordering Information

Biological Activity

Benzo-15-crown-5-ether is a macrocyclic polyether and synthetic ionophore that functions as a chelating ligand for alkali metal cations, particularly sodium and potassium ions. By selectively binding these metal cations through oxygen atom coordination, it modulates ion transport across lipid membranes and influences cellular ion homeostasis. These chelating properties enable its utility in phase-transfer processes and chemical biology applications. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 54 mg/mL (201.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 54 mg/mL
Water 10 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.