CAS No. 5003-48-5

Batch: Purity:99.93
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Benorylate Chemical Structure
Chemical Structure
Check the Benorylate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 5003-48-5
Molecular Formula

C17H15NO5
Molecular Weight (MW) 313.30
SMILES CC(=O)NC1=CC=C(C=C1)OC(=O)C2=CC=CC=C2OC(=O)C

Biological Activity

Benorylate is an esterification product of acetylsalicylic acid and paracetamol with anti-inflammatory, analgesic, and antipyretic properties. Upon metabolic hydrolysis, it liberates active moieties that inhibit cyclooxygenase (COX) enzymes, thereby suppressing downstream prostaglandin synthesis. This blockade modulates inflammatory signaling pathways, leading to reduced inflammatory mediator production, pain signal attenuation, and pyresis suppression in preclinical models.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 62 mg/mL (197.89 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.