CAS No. 621-72-7
Batch:
Purity:99.46
Chemical Structure
Check the
Bendazol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 621-72-7 | |
|---|---|---|
| Molecular Formula |
C14H12N2 |
|
| Molecular Weight (MW) | 208.26 | |
| SMILES | C(C1=NC2=CC=CC=C2[NH]1)C3=CC=CC=C3 |
Bendazol is a hypotensive compound that enhances nitric oxide (NO) synthase activity in renal glomeruli and collecting tubules. It suppresses the upregulation of hypoxia-inducible factor-1α (HIF-1α) and inhibits the progression of form-deprivation myopia. By modulating NO synthase signaling and hypoxia-inducible pathways, Bendazol exerts vasodilatory effects and regulates cellular responses to hypoxic conditions.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
42 mg/mL
(201.67 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 42 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.