Target Selectivity of KD025 (Belumosudil)
| Key Target | IC50 | Description | Reference |
|---|---|---|---|
| ROCK2 | 100 nM | half-maximal inhibitory concentrations (IC50s) | PMC11514143 |
| ROCK1 | 3 µM | half-maximal inhibitory concentrations (IC50s) | PMC11514143 |
| ROCK1 | 24 µM | -- | PMC12009310 |
| ROCK2 | 24 µM | -- | PMC12009310 |
Check the
KD025 (Belumosudil)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Cell-free Assays (IC50/Ki) for KD025 (Belumosudil)
| Key Target | IC50 (Cell-free) | Description | Reference |
|---|---|---|---|
| ROCK2 | 105 nM | Enzyme activity assay | Download PDF |
| ROCK1 | 24 µM | Enzyme activity assay | Download PDF |
Cell-based Assay (IC50) for KD025 (Belumosudil)
| Cell Type | IC50 (Cell-based) | Description | Reference |
|---|---|---|---|
| No published data available. | |||
Jump to
- KD025 (Belumosudil) Mechanism of Action: ROCK2 Inhibition in T Cells Research
- KD025 (Belumosudil) Clinical Trials
- KD025 (Belumosudil) Working Concentration | Cell Culture | Treatment
- KD025 (Belumosudil) Solubility in DMSO
- KD025 (Belumosudil) Stock Solution
- KD025 (Belumosudil) Storage
- KD025 (Belumosudil) Stability
- KD025 (Belumosudil) Combination Database
- KD025 (Belumosudil) Molecular Weight
- KD025 (Belumosudil) SMILES
- KD025 (Belumosudil) CAS Number
- KD025 (Belumosudil) Chemical Structure (2D and 3D)
- KD025 (Belumosudil) IC50 for Cell-based and Cell-free Assays
- KD025 (Belumosudil) Cayman (17055)? Try a better option.
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- KD025 (Belumosudil) SDS｜MSDS