CAS No. 198481-32-2
Batch:
Purity: 95.305
Chemical Structure
Check the
Bazedoxifene
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 198481-32-2 | |
|---|---|---|
| Molecular Formula |
C30H34N2O3 |
|
| Molecular Weight (MW) | 470.60 |
Bazedoxifene is a selective estrogen receptor modulator that targets ERα and ERβ. It disrupts IL-6/GP130 protein-protein interactions and suppresses STAT3 signaling pathways in cancer cells. Consequently, bazedoxifene suppresses cancer cell viability, attenuates colony formation, and induces apoptosis, ultimately leading to reduced tumor growth in preclinical cancer models.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
94 mg/mL
(199.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 24 mg/mL |
| Water | Insoluble |
| DMSO |
94 mg/mL
(199.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 6 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.