CAS No. 298708-79-9
Batch:
Purity:99.03
Chemical Structure
Check the
Bay 41-4109 racemate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | methyl 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate | |
|---|---|---|
| CAS Number | 298708-79-9 | |
| Molecular Formula |
C18H13ClF3N3O2 |
|
| Molecular Weight (MW) | 395.76 | |
| SMILES | CC1=C(C(N=C(N1)C2=C(C=C(C=N2)F)F)C3=C(C=C(C=C3)F)Cl)C(=O)OC | |
| InChIKey | FVNJBPMQWSIGJK-UHFFFAOYSA-N |
Bay 41-4109 racemate is a heteroaryldihydropyrimidine antiviral agent that inhibits human hepatitis B virus (HBV) with an IC50 of. It acts as a capsid assembly modulator by targeting the HBV core protein, which destabilizes proper viral capsids and accelerates core protein degradation. This mechanism blocks pregenomic RNA packaging, ultimately preventing viral DNA synthesis and HBV replication in host cells. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
79 mg/mL
(199.61 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 11 mg/mL |
| Water | ˂1 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.