CAS No. 10127-02-3
| IUPAC Name | zinc;3-N,3-N,6-N,6-N-tetramethylacridine-3,6-diamine;dichloride;hydrochloride | |
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| CAS Number | 10127-02-3 | |
| Molecular Formula |
C17H20ClN3 ·HCl·1/2ZnCl2 |
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| Molecular Weight (MW) | 369.96 | |
| InChIKey | VADJQOXWNSPOQA-UHFFFAOYSA-L |
Basic Orange 14 (Acridine Orange hemi (zinc chloride) salt) is an RNA polymerase inhibitor and cell-permeable metachromatic fluorescent dye that binds and stains DNA and RNA. Upon intercalating into nucleic acids, it exhibits differential fluorescence, emitting green light when bound to double-stranded DNA and red light when bound to single-stranded RNA or DNA. This interaction inhibits RNA polymerase-mediated nucleic acid synthesis, impairing transcription and altering cellular chromatin dynamics. [1]
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