CAS No. 85233-19-8
Batch:
Purity:
Chemical Structure
Check the
BAPTA
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 2-[2-[2-[2-[bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)anilino]acetic acid | |
|---|---|---|
| CAS Number | 85233-19-8 | |
| Molecular Formula |
C22H24N2O10 |
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| Molecular Weight (MW) | 476.43 | |
| InChIKey | FTEDXVNDVHYDQW-UHFFFAOYSA-N |
Biological Activity
BAPTA is a selective calcium chelator and buffering agent featuring high selectivity for Ca²⁺ over Mg²⁺, fast association kinetics, and minimal pH sensitivity. By rapidly chelating free cytosolic calcium, BAPTA disrupts Ca²⁺-dependent signaling pathways, preventing calcium release from intracellular stores and blocking calcium influx through ion channels to modulate downstream cellular physiological processes. [1]
How to Prepare Stock Solution?
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Concentration
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Mass
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Solubility
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All in vitro solubility values are batch-tested experimental data (non-literature values).
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Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.