CAS No. 81732-46-9
Batch:
Purity:99.94
Chemical Structure
Check the
Bambuterol HCl
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 81732-46-9 | |
|---|---|---|
| Molecular Formula |
C18H29N3O5.HCl |
|
| Molecular Weight (MW) | 403.90 | |
| SMILES | CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)O.Cl |
Biological Activity
Bambuterol HCl is a carbamate prodrug of terbutaline that acts as a selective β2-adrenoceptor agonist and a potent inhibitor of butyrylcholinesterase. Upon metabolic conversion, it selectively activates β2-adrenergic receptors, stimulating adenylyl cyclase and increasing intracellular cAMP levels. This activation leads to smooth muscle relaxation, bronchodilation, and inhibition of inflammatory mediator release in respiratory tissues. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
80 mg/mL
(198.06 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 72 mg/mL |
| Ethanol | 28 mg/mL |
| DMSO |
80 mg/mL
(198.06 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 80 mg/mL |
| Ethanol | 8 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
Jump to
Note: Technical data last updated: Sep 1, 2026.