CAS No. 891025-25-5
Batch:
Purity:99.99
Chemical Structure
Check the
BAMB-4
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-(1,2-benzoxazol-3-yl)-4-methylbenzamide | |
|---|---|---|
| CAS Number | 891025-25-5 | |
| Molecular Formula |
C15H12N2O2 |
|
| Molecular Weight (MW) | 252.27 | |
| SMILES | CC1=CC=C(C=C1)C(=O)NC2=NOC3=CC=CC=C23 | |
| InChIKey | IEPCQLHHUYRTEY-UHFFFAOYSA-N |
BAMB-4 (ITPKA-IN-C is a membrane-permeable small-molecule inhibitor targeting inositol-1,4,5-trisphosphate 3-kinase A (ITPKA). Pharmacological inhibition of ITPKA by BAMB-4 interferes with intracellular inositol phosphate signaling and impairs actin cytoskeleton remodeling. Downstream, this disruption of cytoskeletal reorganization decreases cancer cell motility, adhesion, and invasion, leading to reduced tumor cell migration and impaired metastatic dissemination. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
50 mg/mL
(198.2 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.