CAS No. 1985606-14-1

Batch: Purity:99.92
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Baloxavir marboxil Chemical Structure
Chemical Structure
Check the Baloxavir marboxil product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name [(3R)-2-[(11S)-7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl]-9,12-dioxo-5-oxa-1,2,8-triazatricyclo[8.4.0.03,8]tetradeca-10,13-dien-11-yl]oxymethyl methyl carbonate
CAS Number 1985606-14-1
Molecular Formula

C27H23F2N3O7S
Molecular Weight (MW) 571.55
SMILES COC(=O)OCOC1=C2C(=O)N3CCOCC3N(N2C=CC1=O)C4C5=C(CSC6=CC=CC=C46)C(=C(C=C5)F)F
InChIKey RZVPBGBYGMDSBG-GGAORHGYSA-N

Ordering Information

Biological Activity

Baloxavir marboxil is a prodrug converted into baloxavir, a potent inhibitor of influenza virus cap-dependent endonuclease. By targeting the PA subunit of the viral RNA polymerase, baloxavir blocks the cap-snatching process required for viral mRNA synthesis. This inhibition suppresses viral transcription and replication, significantly impairing the proliferation of both influenza A and influenza B viruses in host cells. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (174.96 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 7 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.