CAS No. 34539-65-6

Batch: Purity:98.73
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β,β-dimethyl-acryl-alkannin Chemical Structure
Chemical Structure
Check the β,β-dimethyl-acryl-alkannin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 34539-65-6
Molecular Formula

C21H22O6
Molecular Weight (MW) 370.40
SMILES CC(C)=CCC(OC(=O)C=C(C)C)C1=CC(=O)C2=C(C(=CC=C2O)O)C1=O

Biological Activity

β,β-Dimethyl-acryl-alkannin (AN-I) is a natural naphthoquinone derivative isolated from the roots of Arnebia nobilis that exhibits potential anti-aging, anti-inflammatory, and antitumor biological activities. It modulates cellular oxidative stress responses and signaling cascades associated with cell survival and apoptosis, leading to the inhibition of cancer cell proliferation and promotion of programmed cell death. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 8 mg/mL (21.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Chen SH. Curr Med Chem. 2002;9(9):899-912.

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Note: Technical data last updated: Sep 1, 2026.