SMILES:
CC(=O)NC1CCCC(C1)C(=O)NC2=NC=C(C(=C2)C3=C4CC(CN4N=C3)(C)C)Cl
Chemical Structure
Check the
AZD4573
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | cis-(1S,3R)-3-acetamido-N-[5-chloro-4-(5,5-dimethyl-4,6-dihydropyrrolo[2,1-e]pyrazol-3-yl)-2-pyridinyl]cyclohexane-1-carboxamide | |
|---|---|---|
| CAS Number | 2057509-72-3 | |
| Molecular Formula |
C22H28ClN5O2 |
|
| Molecular Weight (MW) | 429.94 | |
| SMILES | CC(=O)NC1CCCC(C1)C(=O)NC2=NC=C(C(=C2)C3=C4CC(CN4N=C3)(C)C)Cl | |
| InChIKey | AVIWDYSJSPOOAR-LSDHHAIUSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
86 mg/mL
(200.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 86 mg/mL |
| Water | Insoluble |
| DMSO |
86 mg/mL
(200.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 86 mg/mL |
| Water | Insoluble |
| DMSO |
86 mg/mL
(200.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 86 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- AZD4573 Mechanism of Action: CDK9 Inhibition in Hematological Cancer Cell Research
- AZD4573 Clinical Trials
- AZD4573: Selectivity & Specificity
- AZD4573 Working Concentration | Cell Culture | Treatment
- AZD4573 Solubility in DMSO
- AZD4573 Stock Solution
- AZD4573 Storage
- AZD4573 Stability
- AZD4573 Molecular Weight
- AZD4573 CAS Number
- AZD4573 Chemical Structure (2D and 3D)
- AZD4573 IC50 for Cell-based and Cell-free Assays
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- AZD4573 SDS|MSDS
Note: Technical data last updated: Sep 1, 2026.