Molecular Weight: 459.90 g/mol
Chemical Structure
Check the
Zorifertinib (AZD3759)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
91 mg/mL
(197.86 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 20 mg/mL |
| Water | Insoluble |
| DMSO |
92 mg/mL
(200.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 44 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
| IUPAC Name | [4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl] (2R)-2,4-dimethylpiperazine-1-carboxylate | |
|---|---|---|
| CAS Number | 1626387-80-1 | |
| Molecular Formula |
C22H23ClFN5O3 |
|
| Molecular Weight (MW) | 459.90 | |
| SMILES | CC1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C | |
| InChIKey | MXDSJQHFFDGFDK-CYBMUJFWSA-N |
- Zorifertinib (AZD3759) Clinical Trials
- Zorifertinib (AZD3759) Solubility in DMSO
- Zorifertinib (AZD3759) Stock Solution
- Zorifertinib (AZD3759) Storage
- Zorifertinib (AZD3759) Stability
- Zorifertinib (AZD3759) SMILES
- Zorifertinib (AZD3759) CAS Number
- Zorifertinib (AZD3759) Chemical Structure (2D and 3D)
- Zorifertinib (AZD3759) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.