CAS No. 76801-85-9
Batch:
Purity:98
Chemical Structure
Check the
Azathramycin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 76801-85-9 | |
|---|---|---|
| Molecular Formula |
C37H70N2O12 |
|
| Molecular Weight (MW) | 734.96 | |
| SMILES | CCC1C(C(C(NCC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O |
Azathramycin (also known as azaerythromycin A) is a macrolide antibiotic containing cladinose that functions as a bacterial protein synthesis inhibitor. It targets the 50S ribosomal subunit to block peptide chain elongation during translation. By disrupting ribosomal activity, azathramycin inhibits bacterial translation pathways and exhibits antimicrobial activity against susceptible Gram-positive and Gram-negative pathogens.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Ethanol | 100 mg/mL |
| DMSO |
50 mg/mL
(68.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.