CAS No. 495-02-3
Batch:
Purity:99.62
Chemical Structure
Check the
Auraptene
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 7-[(2E)-3,7-dimethylocta-2,6-dienoxy]chromen-2-one | |
|---|---|---|
| CAS Number | 495-02-3 | |
| Molecular Formula |
C19H22O3 |
|
| Molecular Weight (MW) | 298.38 | |
| SMILES | CC(=CCCC(=CCOC1=CC2=C(C=C1)C=CC(=O)O2)C)C | |
| InChIKey | RSDDHGSKLOSQFK-RVDMUPIBSA-N |
Auraptene is a natural citrus-derived coumarin with anticarcinogenic, anti-inflammatory, and neuroprotective properties. It inhibits matrix metalloproteinase 2 (MMP-2) and downregulates key inflammatory mediators, including IL-6, IL-8, and chemokine (C-C motif) ligand-5 (CCL5). Through modulation of extracellular matrix remodeling and inflammatory cytokine signaling pathways, Auraptene exerts antigenotoxic and antihelicobacter effects across various preclinical cellular and animal models.
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
59 mg/mL
(197.73 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
10 mg/mL
(33.51 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.