CAS No. 55-48-1
Batch:
Purity:99.85
Chemical Structure
Check the
Atropine sulfate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | bis([(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate);sulfuric acid | |
|---|---|---|
| CAS Number | 55-48-1 | |
| Molecular Formula |
C34H46N2O6.H2SO4 |
|
| Molecular Weight (MW) | 676.82 | |
| SMILES | CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.OS(=O)(=O)O | |
| InChIKey | HOBWAPHTEJGALG-JKCMADFCSA-N |
Atropine sulfate is a natural tropane alkaloid that functions as a competitive antagonist of muscarinic acetylcholine receptors. By blocking endogenous cholinergic signaling, it inhibits parasympathetic nerve stimulation and modulates downstream G protein-coupled receptor pathways, including cyclic AMP accumulation and phosphoinositide turnover. This inhibition leads to decreased smooth muscle contraction, suppression of glandular secretions, and altered cardiac conduction. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 100 mg/mL |
| DMSO |
18 mg/mL
(26.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.