CAS No. 102130-43-8
Batch:
Purity:99.94
Chemical Structure
Check the
Atractyloside potassium salt
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | dipotassium;[(2S,3R,4R,5R,6R)-2-[[(1R,4R,5R,7R,9R,10S,13R,15S)-5-carboxy-15-hydroxy-9-methyl-14-methylidene-7-tetracyclo[11.2.1.01,10.04,9]hexadecanyl]oxy]-6-(hydroxymethyl)-3-(3-methylbutanoyloxy)-5-sulfonatooxyoxan-4-yl] sulfate | |
|---|---|---|
| CAS Number | 102130-43-8 | |
| Molecular Formula |
C30H44K2O16S2 |
|
| Molecular Weight (MW) | 802.99 | |
| SMILES | [K+].[K+].CC(C)CC(=O)OC1C(OC2CC(C3CCC45CC(CCC4C3(C)C2)C(=C)C5O)C(O)=O)OC(CO)C(O[S]([O-])(=O)=O)C1O[S]([O-])(=O)=O | |
| InChIKey | IUCNQFHEWLYECJ-VCQILIGCSA-L |
Atractyloside potassium salt is a toxic diterpenoid glycoside that acts as a potent inhibitor of mitochondrial adenine nucleotide translocators (ADP/ATP carriers). By blocking ADP/ATP exchange across the inner mitochondrial membrane, it disrupts oxidative phosphorylation and promotes mitochondrial permeability transition pore opening. This disruption impairs cellular energy metabolism and induces apoptotic cell death in eukaryotic cells. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(124.53 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
100 mg/mL
(124.53 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Atractyloside potassium salt Solubility in DMSO
- Atractyloside potassium salt Stock Solution
- Atractyloside potassium salt Storage
- Atractyloside potassium salt Stability
- Atractyloside potassium salt Molecular Weight
- Atractyloside potassium salt SMILES
- Atractyloside potassium salt Chemical Structure (2D and 3D)
- Atractyloside potassium salt SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.