CAS No. 30315-93-6

Asymmetric dimethylarginine Chemical Structure
Chemical Structure
Check the Asymmetric dimethylarginine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2S)-2-amino-5-[[amino(dimethylamino)methylidene]amino]pentanoic acid
CAS Number 30315-93-6
Molecular Formula

C8H18N4O2

Molecular Weight (MW) 202.25
InChIKey YDGMGEXADBMOMJ-LURJTMIESA-N

Biological Activity

Asymmetric dimethylarginine is an endogenous methylarginine and competitive inhibitor of nitric oxide synthase (NOS). By suppressing NOS activity and decreasing endothelial nitric oxide production, it disrupts NO-mediated signaling, impairs vascular relaxation, and promotes endothelial dysfunction. These cellular downstream effects lead to altered vascular tone and increased oxidative stress in vascular cell models. [1]

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Note: Technical data last updated: Sep 1, 2026.