CAS No. 185951-07-9
Batch:
Purity:99.81
Chemical Structure
Check the
Asimadoline hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 185951-07-9 | |
|---|---|---|
| Molecular Formula |
C27H30N2O2.ClH |
|
| Molecular Weight (MW) | 451 | |
| SMILES | CN(C(CN1CCC(C1)O)C2=CC=CC=C2)C(=O)C(C3=CC=CC=C3)C4=CC=CC=C4 |
Asimadoline hydrochloride is an orally active and peripherally selective κ-opioid receptor agonist. By selectively binding to peripheral κ-opioid receptors, it inhibits pain signal transmission and modulates visceral sensory pathways. This targeted activation attenuates hyperalgesia and inflammation in preclinical models of visceral hypersensitivity, providing localized antinociceptive effects without producing typical central nervous system-mediated side effects. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
90 mg/mL
(199.55 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 11 mg/mL |
| Water | 3 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Asimadoline hydrochloride Solubility in DMSO
- Asimadoline hydrochloride Stock Solution
- Asimadoline hydrochloride Storage
- Asimadoline hydrochloride Stability
- Asimadoline hydrochloride Molecular Weight
- Asimadoline hydrochloride SMILES
- Asimadoline hydrochloride Chemical Structure (2D and 3D)
- Asimadoline hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.