Molecular Weight: 723.9 g/mol
Chemical Structure
Check the
Vepdegestrant (ARV-471)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(138.14 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
| IUPAC Name | (3S)-3-[6-[4-[[1-[4-[(1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]phenyl]piperidin-4-yl]methyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione | |
|---|---|---|
| CAS Number | 2229711-68-4 | |
| Molecular Formula |
C45H49N5O4 |
|
| Molecular Weight (MW) | 723.9 | |
| InChIKey | TZZDVPMABRWKIZ-XMOGEVODSA-N |
- Vepdegestrant (ARV-471) Clinical Trials
- Vepdegestrant (ARV-471) Solubility in DMSO
- Vepdegestrant (ARV-471) Stock Solution
- Vepdegestrant (ARV-471) Storage
- Vepdegestrant (ARV-471) Stability
- Vepdegestrant (ARV-471) CAS Number
- Vepdegestrant (ARV-471) Chemical Structure (2D and 3D)
- Vepdegestrant (ARV-471) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.