CAS No. 528-92-7
Batch:
Purity:99.47
Chemical Structure
Check the
Apronal
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 528-92-7 | |
|---|---|---|
| Molecular Formula |
C9H16N2O2 |
|
| Molecular Weight (MW) | 184.24 | |
| SMILES | CC(C)C(CC=C)C(=O)NC(=O)N |
Apronal (Allylisopropylacetylurea) is a monoureide derivative that functions as a sedative and hypnotic agent. It acts as a central nervous system depressant by modulating GABAergic signaling pathways to induce sedative phenotypes. In liver tissue models, Apronal promotes the degradation of cytochrome P450 enzymes, leading to altered heme biosynthesis and reduced microsomal monooxygenase activity. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
37 mg/mL
(200.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 18 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.