CAS No. 767299-99-0

AP-503 Chemical Structure
Chemical Structure
Check the AP-503 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 767299-99-0
Molecular Formula

C24H31N3O4

Molecular Weight (MW) 425.52

Ordering Information

Biological Activity

AP-503 is a potent selective agonist of the adhesion G-protein coupled receptor GPR133 (ADGRD1). Activation of GPR133 stimulates downstream Gs protein-mediated signaling pathways, elevating intracellular cyclic AMP levels and regulating downstream cellular processes. Through targeted receptor activation, AP-503 serves as a valuable tool for investigating adhesion GPCR signaling mechanisms and holds potential utility in research related to muscle-related disorders and vestibular dysfunction. [1]

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Note: Technical data last updated: Sep 1, 2026.