CAS No. 91531-30-5
Batch:
Purity:99.46
Chemical Structure
Check the
Antineoplaston A10
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-[(3S)-2,6-dioxopiperidin-3-yl]-2-phenylacetamide | |
|---|---|---|
| CAS Number | 91531-30-5 | |
| Molecular Formula |
C13H14N2O3 |
|
| Molecular Weight (MW) | 246.26 | |
| SMILES | C1CC(=O)NC(=O)C1NC(=O)CC2=CC=CC=C2 | |
| InChIKey | OQGRFQCUGLKSAV-JTQLQIEISA-N |
Antineoplaston A10 (Phenylacetylglutamine) is an antineoplastic agent that targets the RAS signaling pathway. By inhibiting RAS expression and activity, it interrupts downstream cascade signaling and promotes cell apoptosis in preclinical cancer models. These molecular mechanisms impair cell survival and proliferation across various tumor cell types, contributing to suppressed oncogenic growth. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
49 mg/mL
(198.97 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
49 mg/mL
(198.97 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.