CAS No. 916918-84-8

Batch: Purity:99.88
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Ansofaxine hydrochloride Chemical Structure
Chemical Structure
Check the Ansofaxine hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name [4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenyl] 4-methylbenzoate;hydrochloride
CAS Number 916918-84-8
Molecular Formula

C24H31NO3.ClH
Molecular Weight (MW) 417.97
SMILES CC1=CC=C(C=C1)C(=O)OC2=CC=C(C=C2)C(CN(C)C)C3(CCCCC3)O.Cl
InChIKey BVWFJKQJRNSYCR-UHFFFAOYSA-N

Ordering Information

Biological Activity

Ansofaxine hydrochloride is a triple reuptake inhibitor that inhibits serotonin, dopamine, and norepinephrine reuptake. By blocking these monoamine transporters, it suppresses the clearance of monoamine neurotransmitters and elevates synaptic concentrations of serotonin, dopamine, and norepinephrine. This modulation enhances monoaminergic neurotransmission and downstream neuronal signaling cascades, leading to altered neurobehavioral phenotypes and regulated central nervous system activity. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 84 mg/mL (200.97 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 42 mg/mL
Water 3 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.