CAS No. 55449-49-5

Batch: Purity:99.79
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Anisodamine Hydrobromide Chemical Structure
Chemical Structure
Check the Anisodamine Hydrobromide product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 55449-49-5
Molecular Formula

C17H24BrNO4
Molecular Weight (MW) 386.28
SMILES CN1C2CC(CC1C(C2)O)OC(=O)C(CO)C3=CC=CC=C3.Br

Ordering Information

Biological Activity

Anisodamine Hydrobromide is a naturally occurring atropine derivative that functions as an antagonist of muscarinic acetylcholine receptors and α1-adrenergic receptors, while displaying pronounced anti-inflammatory activity. By inhibiting receptor-mediated signaling pathways, anisodamine reduces vascular resistance and suppresses pro-inflammatory mediator production. These multi-target inhibitory effects serve to improve microcirculation, mitigate inflammatory tissue damage, and protect microvascular function in various pathophysiological condition models.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 77 mg/mL (199.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 77 mg/mL
Ethanol 30 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.