CAS No. 195615-84-0
Batch:
Purity:99.9
Chemical Structure
Check the
Anavex 2-73 HCl
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-(2,2-diphenyloxolan-3-yl)-N,N-dimethylmethanamine;hydrochloride | |
|---|---|---|
| CAS Number | 195615-84-0 | |
| Molecular Formula |
C19H24ClNO |
|
| Molecular Weight (MW) | 317.85 | |
| SMILES | CN(C)CC1CCOC1(C2=CC=CC=C2)C3=CC=CC=C3.Cl | |
| InChIKey | FEQOLYDPQKHFTD-UHFFFAOYSA-N |
Anavex 2-73 HCl (Blarcamesine) is an aminotetrahydrofuran derivative functioning as a mixed muscarinic receptor and sigma-1 receptor agonist with an IC50 of. Target activation modulates downstream neuroprotective pathways to alleviate oxidative stress, mitochondrial dysfunction, and neuroinflammation. Consequently, this compound promotes neuronal survival and enhances cognitive performance in preclinical models of neurodegenerative disorders. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
64 mg/mL
(201.35 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 64 mg/mL |
| Ethanol | 3 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.