CAS No. 2444815-84-1
Chemical Structure
Check the
AMXT-1501 tetrahydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 2444815-84-1 | |
|---|---|---|
| Molecular Formula |
C32H68N6O2.4ClH |
|
| Molecular Weight (MW) | 714.77 |
AMXT-1501 tetrahydrochloride is an orally bioavailable inhibitor of the polyamine transport system. By blocking external polyamine uptake, the compound acts synergistically with ornithine decarboxylase inhibitors like DFMO to simultaneously disrupt intracellular polyamine synthesis and import pathways. This dual inhibition effectively starves cancer cells of essential polyamines, suppressing cell proliferation and reinvigorating anti-tumor immune responses in preclinical cancer models. [1]
|
Concentration
Volume
Mass
|
|---|
Note: Technical data last updated: Sep 1, 2026.