CAS No. 88150-47-4

Batch: Purity:99.89
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Amlodipine maleate Chemical Structure
Chemical Structure
Check the Amlodipine maleate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (Z)-but-2-enedioic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS Number 88150-47-4
Molecular Formula
C24H29ClN2O9
Molecular Weight (MW) 524.95
SMILES CCOC(=O)C1=C(COCCN)NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C.OC(=O)\C=C/C(O)=O
InChIKey TZNOWAJJWCGILX-BTJKTKAUSA-N

Ordering Information

Biological Activity

Amlodipine maleate is a long-acting dihydropyridine calcium channel blocker that selectively inhibits L-type voltage-gated calcium channels in vascular smooth muscle and cardiac cells. By blocking transmembrane calcium influx, amlodipine inhibits calcium-dependent contractile responses in vascular smooth muscle cells, leading to peripheral vasodilation and reduced vascular resistance. Inhibiting intracellular calcium accumulation downregulates signaling pathways governing vascular tone and smooth muscle constriction.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (190.49 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.