CAS No. 37517-28-5
Chemical Structure
Check the
Amikacin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 37517-28-5 | |
|---|---|---|
| Molecular Formula |
C22H43N5O13 |
|
| Molecular Weight (MW) | 585.60 |
Biological Activity
Amikacin is a semisynthetic aminoglycoside derivative of kanamycin-A that acts as a broad-spectrum antibacterial agent. It targets the bacterial ribosomal A-site within the 30S subunit, causing codon misreading and inhibition of protein synthesis. This interference disrupts cellular translation and division, exhibiting potent bactericidal activity against Gram-negative bacteria, mycobacteria, and Nocardia species. [1]
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Note: Technical data last updated: Sep 1, 2026.