CAS No. 6790-58-5

Batch: Purity:98
(-)-Ambroxide Chemical Structure
Chemical Structure
Check the (-)-Ambroxide product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 6790-58-5
Molecular Formula

C16H28O

Molecular Weight (MW) 236.39
SMILES CC1(CCCC2(C1CCC3(C2CCO3)C)C)C

Ordering Information

Biological Activity

(-)-Ambroxide is a naturally occurring terpenoid and key ambergris fragrance constituent that functions as a selective odorant ligand for olfactory G protein-coupled receptors (GPCRs). Interaction with olfactory receptors stimulates downstream heterotrimeric G protein signaling pathways, activating adenylyl cyclase to increase intracellular cyclic AMP (cAMP) levels and trigger neuronal depolarization for olfactory transduction. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 31 mg/mL (131.13 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.